6 results
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT/PTT ... Subcutaneous dissecting hematoma ... INR < 2.3 - APTT ... causes #treatment #management ... #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... Warfarin • Acute DIC ... disease • Acute DIC ... Bruising #Hemostasis #Differential ... #Diagnosis #Hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Abnormal PT and/or aPTT ... Acquired deficiency ... intravascular coagulation (DIC ... Causes #diagnosis #differential ... #hematology #coagulation
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... - History of bleeding ... epistaxis, gingival bleeding ... cases: INR/PT, aPTT ... evaluation: not required
Postpartum Hemorrhage - Differential Diagnosis and Management 
Uterine Atony (80%) - Most PPH Will respond to
Postpartum Hemorrhage - Differential ... Diagnosis and Management ... epinephrine prn DIC ... fibrinogen, PT/PTT ... #Diagnosis #Management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
the secondary or acquired ... purpura to mucosal bleeding ... Hypofibrinogenemia • ↑ PT ↑ PTT ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology