15 results
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential ... Brucellosis - Viruses: HIV ... Effusions: - Hematologic ... Osteochondroma Hematologic ... Effusions #causes #differential
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
predispose to other orthopedic ... common sites: hip ... • Differentiate ... #differential # ... diagnosis #causes #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Clinical features ... involvement Differential ... Lymphomas • Other hematologic ... oncology #diagnosis #differential ... #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Clinical triad ... fraction < 20% Differential ... Coxsackie, CMV, EBV, HIV ... management #treatment #rheumatology
Bone Deformity / Limp - Differential Diagnosis Algorithm 
Infection
 • Septic Arthritis
 • Cortical Hypertrophy
 •
Deformity / Limp - Differential ... Joint • Hip Dysplasia ... Knee Joint • ... Deformity #Limp #MSK #Differential ... Diagnosis #Algorithm #Orthopedics
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... - HIV infection ... multifactorial mechanisms Hematologic ... , Gaucher disease ... Classification #Diagnosis #Differential
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... Hepatic infarcts, Hematomas ... BrighamChiefs #Liver #Disease ... #Pregnancy #hepatology ... hepatitis #comparison #differential
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Allopecia - Differential ... Capitis - Skin Disease ... of any comorbid disease ... texture at bald spots ... loss #alopecia #Differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Disease ... Viral Infection Clinical ... Mycoplasma, EBV, HIV ... younger pts) Differential ... hemolytic #anemia #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... lymphoproliferative syndrome Clinical ... • Malar rash - spares