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diagnosis obstetrics aflp causes hepatitis obgyn pregnancy coagulation comparison disease disseminated fatty injury intravascular pathophysiology postpartum pph treatment
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Hepatic infarcts, Hematomas ... extensive necrosis and hemorrhage ... DIC • Aminotransferases ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
- Differential ... Diagnosis Algorithm ... Vaginal laceration / hematoma ... purpura (TTP) • HELLP ... intravascular coagulation (DIC
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
rapidly develops (DIC ... Antithrombin Ill • Ultrasound ... infiltration) Differential ... Preeclampsia, HELLP ... #Pregnancy #hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Acral cyanosis • Hemorrhagic ... Subcutaneous dissecting hematoma ... • Severe Liver ... causes #treatment #management ... #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... • Pregnancy: HELLP ... hemolysis, bleeding, hematoma ... #hepatology
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