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aflp hepatitis obstetrics coagulation comparison dermatology disease disseminated fatty hellp injury intravascular obgyn palpable pathophysiology purpura treatment
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Hepatic infarcts, Hematomas ... extensive necrosis and hemorrhage ... DIC • Aminotransferases ... #hepatology #obstetrics ... #diagnosis #icp
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
red to purple, hemorrhagic ... deficiency • Liver ... #Diagnosis #hematology ... #rheumatology # ... palpable #nonpalpable
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... rapidly develops (DIC ... Antithrombin Ill • Ultrasound ... infiltration) Differential ... #Pregnancy #hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Acral cyanosis • Hemorrhagic ... Subcutaneous dissecting hematoma ... • Severe Liver ... #Coagulation #diagnosis ... #management #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Diagnosis Algorithm ... Vascular Causes ... hemolysis, bleeding, hematoma ... #diagnosis #algorithm ... #hepatology
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