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diagnosis obstetrics aflp obgyn coagulation comparison disease disseminated fatty hepatitis pph treatment
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Hepatic infarcts, Hematomas ... extensive necrosis and hemorrhage ... DIC • Aminotransferases ... #hepatology #obstetrics ... hepatitis #comparison #differential
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
range: 18 wks - postpartum ... rapidly develops (DIC ... infiltration) Differential ... Preeclampsia, HELLP ... #Pregnancy #hepatology
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Hemorrhage - Differential ... Vaginal laceration / hematoma ... purpura (TTP) • HELLP ... • Disseminated intravascular ... coagulation (DIC
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Acral cyanosis • Hemorrhagic ... Subcutaneous dissecting hematoma ... • Severe Liver ... #treatment #management ... #hematology
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