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aflp differential hepatology management obgyn pregnancy algorithm comparison disease fatty hematology hemorrhage icp intravascular postpartum pph treatment
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Coagulation (DIC ... organ damage Clinical ... Subcutaneous dissecting hematoma ... • Severe Liver ... #diagnosis #causes
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Vaginal laceration / hematoma ... purpura (TTP) • HELLP ... syndrome • Disseminated ... (DIC) • Anti-coagulation ... #Obstetrics #OBGyn
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Hepatic infarcts, Hematomas ... DIC • Aminotransferases ... Pregnancy #hepatology #obstetrics ... #hepatitis #comparison ... #differential #diagnosis
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... rapidly develops (DIC ... : Viral Hepatitis ... Preeclampsia, HELLP ... Pregnancy #hepatology #obstetrics
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