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liver obstetrics pregnancy causes coagulation comparison differential disseminated fatty hepatitis icp intravascular obgyn pathophysiology treatment
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Hepatic infarcts, Hematomas ... DIC • Aminotransferases ... #Pregnancy #hepatology ... #differential #diagnosis ... #icp #HELLP #AFLP
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
abdominal pain, headache ... rapidly develops (DIC ... Antithrombin Ill • Ultrasound ... Preeclampsia, HELLP ... Liver #Pregnancy #hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Acral cyanosis • Hemorrhagic ... Subcutaneous dissecting hematoma ... • Severe Liver Disease ... #Coagulation #diagnosis ... #hematology
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