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liver algorithm causes jaundice bilirubinemia chemistry cholangitis classification comparison disease hellp injury interpretation lfts obstetrics pbc pregnancy primary rvalue transaminitis
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
hemolytic reactions, hematoma ... hepatocyte damage (eg, hepatitis ... cirrhosis, sepsis ... Classification #diagnosis ... #differential #
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Diagnosis Algorithm ... Erythropoiesis • Hematoma ... Dilatation on Ultrasound ... #Causes #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... : < 1 • Cirrhosis ... hemolysis, bleeding, hematoma ... #hepatology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Hepatic infarcts, Hematomas ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential ... #diagnosis #icp
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
: < 1 • Cirrhosis ... hemolysis, bleeding, hematoma ... liver #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... obstruction • ALP ... bile ducts Differential ... Viral hepatitis, ... #workup #hepatology
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