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liver aflp management obstetrics algorithm coagulation comparison dic disseminated fatty hematology icp injury obgyn treatment
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
infarcts, Hematomas ... #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential ... #diagnosis #icp
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Antithrombin Ill • Ultrasound ... infiltration) Differential ... Hepatitis, Preeclampsia ... , HELLP, Intrahepatic ... #hepatology #obstetrics
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Vascular Causes ... melanoma, myeloma • Pregnancy ... : HELLP • Iatrogenic ... hemolysis, bleeding, hematoma ... #hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... Subcutaneous dissecting hematoma ... • Severe Liver Disease ... #Coagulation #diagnosis
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