8 results
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Pruritus - Generalized ... renal failure/uremia ... Myelodisplastic syndrome ... parasitosis #Pruritus ... #generalized #dermatology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Autoimmune Diseases: • Systemic ... lupus erythematosus ... Differential #Diagnosis #Hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... scarring • Subacute cutaneous ... Malignancy (e.g. hematologic ... Neuropsychiatric systemic ... lymphopenia, low PLT • Anemia
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
gangrenosum • Cutaneous ... neuropathy) • Systemic ... (-) hemolytic anemia ... to cold IgG • Lupus ... Paraproteinemias #Hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary ... renal failure/uremia ... Myelodisplastic syndrome ... #secondary #systemic ... #generalized #dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... lupus erythematosus ... with leukopenia, anemia ... Diagnosis #Management #Hematology ... #Rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
associated with systemic ... Most common extra cutaneous ... , breast CA - Hematologic ... - Lupus - Leukemia ... #diagnosis #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
sweats, bleeding • Pruritis ... - infiltrates (anemia ... violaceous, nontender cutaneous ... • Tumor lysis syndrome ... #Leukemia #Hematology