6 results
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... Nephropathy (low urine pH ... #TumorLysis #Syndrome ... #TLS #Pathophysiology
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
Purple Urine Bag Syndrome ... Indurubin (red) - BWH ... Purple #Urine #Bag #Syndrome ... #PUBS #pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Encephalopathy Syndrome ... Clinico-Radiological Syndrome ... hours or longer/BP ... Etiology: • Pathophysiology ... overaggressive BP
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
- Refeeding syndrome ... demonstrate diminished pH ... Wernicke-Korsakoff Syndrome ... • Korsakoff Syndrome ... beriberi #nutrition #pathophysiology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Guillain-Barre Pathophysiology ... threatening labile BP ... Miller Fisher Syndrome ... Guillain #Barre #Syndrome
Bladder outlet obstruction (BOO)

Functional obstruction may be caused by detrusor-sphincter dyssynergia (DSD), either at the level
associated with pain syndromes ... prostatic enlargement (BPH ... Examination of historical ... prostatic obstruction (BPO ... @DharSaty #BPH