201 results
Coagulation cascade and anticoagulants 

Satyendra Dhar MD, @DharSaty

#coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
Coagulation cascade ... @DharSaty #coagulation ... #coumadin #heparin
Coagulation Cascade - Actions of Anticoagulants
 • Heparin: Unfractionated heparin, Enoxaparin, Daltaparin
 • Fondaparinux
 • Direct
Coagulation Cascade ... Anticoagulants • Heparin ... Unfractionated heparin ... EricsMedicalLectures/ #Coagulation
Coagulation Cascade - Anticoagulant Targets
Here's the brief overview of where the main anticoagulants work on the
Coagulation Cascade ... Protein S) - Heparins ... /ambcarerx #Coagulation
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
commonly used anti-coagulation ... Molecular Weight Heparin
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation ... is simultaneous coagulation ... deficiency) • HIT: Heparin-PF4 ... 100mg/dL) - Heparin ... Intravascular #Coagulation
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Summary of Coagulation ... Medications - Heparin ... EricsMedicalLectures/ #Coagulation
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
unfractionated heparin ... Congenital intrinsic coagulation ... cause e.g. heparin ... thrombin inhibitors, heparin ... intravascular coagulation
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... #Coagulation #Cascade ... Rivaroxaban #Edoxaban #heparin
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm
Blood Loss: >500mL post vaginal delivery OR >1000 mL
intravascular coagulation ... (DIC) • Anti-coagulation ... agents (e.g. heparin
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Pre-analytical cause (e.g. heparin ... thrombin inhibitors, heparin ... differential #hematology #coagulation