1884 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Differential Diagnosis Algorithm ... (ALT or AST > ALP ... Wilsons, Pregnancy - AFLP ... Cholestatic Pattern (ALP ... Transaminitis #Algorithm
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... infiltrates maternal hepatocytes ... iMedEducation #AFLP
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Synthesis: in hepatocyte ... accumulation in hepatocyte ... from albumin upon hepatocyte ... conjugation in hepatocyte ... reuptake into hepatocyte
Pathology - Hepatocyte Pigments

Lipofuschin (H&E) 

Alpha-I-antitrypsin globules (PAS-D) 

Mallory's hyaline / Mallory Denk Bodies 

Giant Mitochondria
Pathology - Hepatocyte ... bilirubinostasis (H&E) #Hepatocyte
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase (ALP ... Differential Diagnosis Algorithm ... ALP: - Enzymes ... - Increased ALP ... Differential #Diagnosis #Algorithm
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
exclusively on hepatocytes ... Within the hepatocyte
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Differential Diagnosis Algorithm ... • Pregnancy - AFLP ... Differential #Diagnosis #Algorithm
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
of Pregnancy (AFLP ... TTPHUS #HELLP #AFLP
Causes of AKI in Pregnancy - Differential Diagnosis
Creatinine - Platelets - Transaminases - LDH - PT/PTT
Nephritis • AFLP
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... • AST/ALT > ALP ... disease - If ALP ... hemolysis) • ALP ... differential #diagnosis #algorithm