128 results
diagnosis differential hepatology algorithm management clinical liver pulmonary interpretation pfts pocus workup function laboratory pathophysiology tests comparison gastroenterology table ultrasound
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
(ALT or AST > ALP ... Wilsons, Pregnancy - AFLP ... Cholestatic Pattern (ALP ... Burak @kwburak #LFTs
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Synthesis: in hepatocyte ... accumulation in hepatocyte ... conjugation in hepatocyte ... reuptake into hepatocyte ... Pathophysiology #Diagnosis #LFTs
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Function Test (LFTs ... for the liver ALP ... Transaminase, ALP ... / ULN ALT) / (ALP ... #FunctionTest #LFTs
An Approach to Jaundice Workup Algorithm by CBC and LFT Pattern - Dr. Eric Strong @DrEricStrong #Jaundice #Workup
Algorithm by CBC and LFT ... Algorithm #Patterns #LFTs
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... (Alk phos/ULN ALP ... • AST/ALT > ALP ... disease • If ALP ... transaminitis #LFTs
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... infiltrates maternal hepatocytes ... iMedEducation #AFLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Pregnancy - AFLP ... • Others #LFTs
Pathology - Hepatocyte Pigments Lipofuschin (H&E) Alpha-I-antitrypsin globules (PAS-D) Mallory's hyaline / Mallory Denk Bodies Giant Mitochondria
Pathology - Hepatocyte ... bilirubinostasis (H&E) #Hepatocyte
Liver Function Tests (LFTs) - Aspartate aminotransferase (AST) - Alanine aminotransferase (ALT) - Alkaline
Function Tests (LFTs ... Function #Tests #LFTs
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
exclusively on hepatocytes ... Within the hepatocyte
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