822 results
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Liver Chemistry ... ALT: • AST: liver ... In liver, 80% of ... primarily within liver ... Synthesis: in hepatocyte
Pathology - Hepatocyte Pigments

Lipofuschin (H&E) 

Alpha-I-antitrypsin globules (PAS-D) 

Mallory's hyaline / Mallory Denk Bodies 

Giant Mitochondria
Pathology - Hepatocyte ... bilirubinostasis (H&E) #Hepatocyte ... Pathology #Hepatology #Clinical
Histologic Features and Prevalence of Nonalcoholic Steatohepatitis (NASH). NASH is a potentially progressive type of nonalcoholic
nonalcoholic fatty liver ... features of NASH in liver-biopsy ... specimens: ballooned hepatocytes ... cirrhosis, and primary liver
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... infiltrates maternal hepatocytes ... → Liver dysfunction ... malaise) → Acute liver ... Maternal Support - Critical
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Findings in Hepatic / Liver ... fold with acute liver ... permanent loss of hepatocytes ... ; in chronic liver ... has exhausted liver
N-Acetyl Cysteine (NAC) Therapy Mechanism of Action: The non-toxic route of APAP metabolism gets saturated in
other routes of liver ... the extent of hepatocyte
Lelli's Test (Lever Sign) for ACL Injury

A fist is placed under the proximal 3rd of the
Lelli's Test (Lever ... #Lellis #Test #Lever ... cruciate #ligament #clinical ... physicalexam #sports #msk
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... Failure (ACLF) Clinical ... of underlying liver ... disease, liver ... support, or liver
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
leaving enterocytes, hepatocytes ... is made in the liver
Explanted liver of a 9-year-old girl with acute liver failure due to acetaminophen overdose.

#liver #transplantation #gross
Explanted liver ... girl with acute liver ... #liver #transplantation ... gross #pathology #clinical