104 results
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Liver Chemistry ... ALT: • AST: liver ... In liver, 80% of ... primarily within liver ... Synthesis: in hepatocyte
Histologic Features and Prevalence of Nonalcoholic Steatohepatitis (NASH). NASH is a potentially progressive type of nonalcoholic
nonalcoholic fatty liver ... features of NASH in liver-biopsy ... specimens: ballooned hepatocytes ... cirrhosis, and primary liver ... HCC #Prevalence #NEJM
Key Clinical Points for Rosacea #Management #Derm #PrimaryCare #Rosacea #Overview #TakeHome #NEJM
Rosacea #Management #Derm ... Overview #TakeHome #NEJM
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
exclusively on hepatocytes ... Within the hepatocyte ... siRNA #Therapy #NEJM
Xanthomas in Familial Hypercholesterolemia #Clinical #PrimaryCare #Derm #Xanthomas #FamilialHypercholesterolemia #Hypercholesterolemia #NEJM
#PrimaryCare #Derm ... Hypercholesterolemia #NEJM
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
develop in fatty hepatocytes ... NonAlcoholicFattyLiverDisease #NEJM
Acanthosis Nigricans and Insulin Resistance - A 27-year-old woman presented with a 2-year history of acanthosis
B) #Clinical #Derm ... Acanthosis #Nigricans #NEJM
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... infiltrates maternal hepatocytes ... → Liver dysfunction ... malaise) → Acute liver ... Transfer to a liver
Panel A shows a patient with erythematotelangiectatic rosacea, in which diffuse erythema and telangiectasia are present
#Clinical #Derm ... PrimaryCare #Rosacea #NEJM
Excoriated papules with honey-colored crusting were present on the abdomen, back (Panel A), arms, and legs.
#Clinical #Derm ... Microscopy #Rash #NEJM