1148 results
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Liver Chemistry ... ALT: • AST: liver ... In liver, 80% of ... primarily within liver ... Synthesis: in hepatocyte
Histologic Features and Prevalence of Nonalcoholic Steatohepatitis (NASH). NASH is a potentially progressive type of nonalcoholic
nonalcoholic fatty liver ... features of NASH in liver-biopsy ... specimens: ballooned hepatocytes ... cirrhosis, and primary liver
Pathology - Hepatocyte Pigments

Lipofuschin (H&E) 

Alpha-I-antitrypsin globules (PAS-D) 

Mallory's hyaline / Mallory Denk Bodies 

Giant Mitochondria
Pathology - Hepatocyte ... bilirubinostasis (H&E) #Hepatocyte
"Liver palms"
Palmar erythema 

#clinical #diagnosis #PhysicalExam 
#hands #liver #hepatology #cirrosis
#photo
"Liver palms" Palmar ... PhysicalExam #hands #liver ... hepatology #cirrosis #photo
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... infiltrates maternal hepatocytes ... → Liver dysfunction ... malaise) → Acute liver ... Transfer to a liver
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
exclusively on hepatocytes ... Within the hepatocyte
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Findings in Hepatic / Liver ... fold with acute liver ... permanent loss of hepatocytes ... ; in chronic liver ... has exhausted liver
N-Acetyl Cysteine (NAC) Therapy Mechanism of Action: The non-toxic route of APAP metabolism gets saturated in
other routes of liver ... the extent of hepatocyte
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
The Liver Consult ... Focus on prior Liver ... MELD - Chronic liver ... disease work up - Liver ... US - Prior liver
Spider Angioma: Dialated superficial arterioles, most commonly associated with advanced liver disease.

Charlie Goldberg, M.D. - UCSD
with advanced liver ... Images #Clinical #Photo