20 results
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
develop in fatty hepatocytes ... #GI #IM #NASH #NAFLD ... NonAlcoholicFattyLiverDisease #NEJM
Histologic Features and Prevalence of Nonalcoholic Steatohepatitis (NASH). NASH is a potentially progressive type of nonalcoholic
liver disease (NAFLD ... specimens: ballooned hepatocytes ... Epidemiology #NASH #NAFLD ... HCC #Prevalence #NEJM
#Pathophys #Neuro #MultipleSclerosis #Topography #NEJM
#Pathophys #Neuro ... MultipleSclerosis #Topography #NEJM
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
exclusively on hepatocytes ... Within the hepatocyte ... siRNA #Therapy #NEJM
A Controlled Trial of Erenumab for Episodic Migraine #EBM #Neuro #Erenumab #Migraine #CGRP #VisualAbstract #NEJM
Migraine #EBM #Neuro ... VisualAbstract #NEJM
Nystagmus from Wernicke’s Encephalopathy - Magnetic resonance imaging of the brain showed T2 hyperintensities involving the
Clinical #Radiology #Neuro ... MRI #Thalamus #NEJM
Cells, Molecules, and Therapies. Shown is a simplified schematic depiction of major cell types within white-matter
#Pathophys #Neuro ... DiseaseModifying #Targets #NEJM
NAFLD Activity Score (NAS)
0–3 for steatosis
0–3 for inflammation
0–2 for ballooning hepatocytes
NAS ≥5 is classified as definitive
NAFLD Activity Score ... for ballooning hepatocytes ... .2020.603926 #NAFLD
Creutzfeldt-Jakob Disease - Magnetic resonance imaging (MRI) revealed hyperintensity of the cortical gyri of the frontal
#Clinical #Neuro ... CreutzfeldJakob #NEJM
Diagnosing Myasthenia Gravis with an Ice Pack - Myasthenia gravis was suspected, and the ice-pack test
Clinical #Diagnosis #Neuro ... MyastheniaGravis #Icepack #NEJM