30 results
Histologic Features and Prevalence of Nonalcoholic Steatohepatitis (NASH). NASH is a potentially progressive type of nonalcoholic
liver disease (NAFLD ... specimens: ballooned hepatocytes ... #Pathology #Epidemiology ... #NASH #NAFLD #NonAlcoholicSteatoHepatitis ... HCC #Prevalence #NEJM
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
develop in fatty hepatocytes ... #GI #IM #NASH #NAFLD ... NonAlcoholicFattyLiverDisease #NEJM
Pathology - Hepatocyte Pigments

Lipofuschin (H&E) 

Alpha-I-antitrypsin globules (PAS-D) 

Mallory's hyaline / Mallory Denk Bodies 

Giant Mitochondria
Pathology - Hepatocyte ... bilirubinostasis (H&E) #Hepatocyte ... #Pigments #Pathology
Assessment of Nonalcoholic Steatohepatitis (NASH) Severity in Patients With Nonalcoholic Fatty
#Diagnosis #Pathology #NAFLD #NASH #Fibrosis #Staging
Fatty #Diagnosis #Pathology ... #NAFLD #NASH #Fibrosis
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
exclusively on hepatocytes ... Within the hepatocyte ... siRNA #Therapy #NEJM
Borrelia recurrentis Infection - Spirochetes were visible (arrows), a finding that suggested louseborne relapsing fever #Clinical
fever #Clinical #Pathology ... Smear #Microscopy #NEJM
NAFLD Activity Score (NAS)
0–3 for steatosis
0–3 for inflammation
0–2 for ballooning hepatocytes
NAS ≥5 is classified as definitive
NAFLD Activity Score ... for ballooning hepatocytes ... .2020.603926 #NAFLD
Excoriated papules with honey-colored crusting were present on the abdomen, back (Panel A), arms, and legs.
Clinical #Derm #Pathology ... Microscopy #Rash #NEJM
African Trypanosomiasis - The examination was notable for the two erythematous lesions, each measuring 3 to
Clinical #Derm #Pathology ... TrypanosomaBrucei #NEJM
Eyelid Melanoma - Despite conservative interventions, the stye had persisted and the skin had become noticeably
C) #Clinical #Pathology ... Melanoma #Microscopy #NEJM