29 results
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
develop in fatty hepatocytes ... #GI #IM #NASH #NAFLD ... NonAlcoholicFattyLiverDisease #NEJM
Histologic Features and Prevalence of Nonalcoholic Steatohepatitis (NASH). NASH is a potentially progressive type of nonalcoholic
liver disease (NAFLD ... specimens: ballooned hepatocytes ... Epidemiology #NASH #NAFLD ... HCC #Prevalence #NEJM
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
exclusively on hepatocytes ... Within the hepatocyte ... siRNA #Therapy #NEJM
NAFLD Activity Score (NAS)
0–3 for steatosis
0–3 for inflammation
0–2 for ballooning hepatocytes
NAS ≥5 is classified as definitive
NAFLD Activity Score ... for ballooning hepatocytes ... .2020.603926 #NAFLD
Herpes Zoster Mandibularis - The lesions were scattered along the area that is innervated by the
#Clinical #Photo ... Mandibularis #Rash #NEJM
A necrotic ulceration was observed on the right side of the tongue. Cervicofacial computed tomography, performed
arteritis #clinical #photo ... Arteritis #tongue #NEJM
Dirofilaria repens- Patient had first noted a nodule below her left eye (Panel A). Five days
repens #clinical #photo ... #NEJM #parasite
Macroglossia in Light-Chain Amyloidosis- Physical examination revealed macroglossia, with indentations from the teeth (Panel A)...A biopsy
amyloidosis #clinical #photo ... AL #lightchain #NEJM
Vibrio vulnificus Infection- At the time of presentation, hemorrhagic bullae measuring 3.5 by 4.5 cm had
#clinical #photo ... #NEJM #vibrio #
Acute Dacryocystitis- A 4-week-old boy was brought to the emergency department after having drainage from both
#NEJM #clinical ... #photo #peds #acute