760 results
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
exclusively on hepatocytes ... Within the hepatocyte ... siRNA #Therapy #NEJM
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Synthesis: in hepatocyte ... accumulation in hepatocyte ... from albumin upon hepatocyte ... conjugation in hepatocyte ... reuptake into hepatocyte
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
develop in fatty hepatocytes ... NonAlcoholicFattyLiverDisease #NEJM
Pathology - Hepatocyte Pigments

Lipofuschin (H&E) 

Alpha-I-antitrypsin globules (PAS-D) 

Mallory's hyaline / Mallory Denk Bodies 

Giant Mitochondria
Pathology - Hepatocyte ... bilirubinostasis (H&E) #Hepatocyte
Regression of Clubbing after Treatment of Lung Cancer #Clinical #PhysicalExam #Radiology #Clubbing #Regression #LungCancer #CT #NEJM
Regression #LungCancer #CT ... #NEJM
Histologic Features and Prevalence of Nonalcoholic Steatohepatitis (NASH). NASH is a potentially progressive type of nonalcoholic
specimens: ballooned hepatocytes ... HCC #Prevalence #NEJM
Emphysematous Prostatitis - Radiography of the kidney, ureter, and bladder showed an atypical focus of gas
computed tomography (CT ... Clinical #Radiology #CT ... #Prostatitis #NEJM
Urinary Tract Tuberculosis - Contrast-enhanced computed tomography (CT) of the abdomen showed mild dilatation of the
computed tomography (CT ... excretory phase on CT ... Radiology #Pathology #CT ... AcidFastBacilli #Microscopy #NEJM
Pulsatile AAA on Abdominal Exam

A 66-year-old man presented with a 2-month history of abdominal bloating and
abdominal mass, which CT ... Clinical #Video #NJEM
Hepatic Portal Venous System Drainage Anatomy
1) Most of the blood from abdominal organs goes into the
is delivered to hepatocytes