798 results
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
exclusively on hepatocytes ... Within the hepatocyte ... siRNA #Therapy #NEJM
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Synthesis: in hepatocyte ... accumulation in hepatocyte ... from albumin upon hepatocyte ... conjugation in hepatocyte ... reuptake into hepatocyte
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
develop in fatty hepatocytes ... NonAlcoholicFattyLiverDisease #NEJM
Pathology - Hepatocyte Pigments

Lipofuschin (H&E) 

Alpha-I-antitrypsin globules (PAS-D) 

Mallory's hyaline / Mallory Denk Bodies 

Giant Mitochondria
Pathology - Hepatocyte ... bilirubinostasis (H&E) #Hepatocyte
Cardiac MRI Demonstrating Electrical Alternans in Pericardial Effusion

Dr Prasad Jain @DrPrasadJain

#Pericardial #Effusion #Cardiac #MRI #Cine #CMRI
Cardiac MRI Demonstrating ... Effusion #Cardiac #MRI ... #Cine #CMRI #Electrical
Creutzfeldt-Jakob Disease - Magnetic resonance imaging (MRI) revealed hyperintensity of the cortical gyri of the frontal
resonance imaging (MRI ... Neuro #Radiology #MRI ... CreutzfeldJakob #NEJM
Swinging Heart within a Large Pericardial Effusion on Cardiac MRI - Electrical Alternans Visualized

Prasad Jain, MD
Effusion on Cardiac MRI ... Alternans #CardiacMRI #CMRI ... cardiology #cardiac #MRI
Nystagmus from Wernicke’s Encephalopathy - Magnetic resonance imaging of the brain showed T2 hyperintensities involving the
Neuro #Wernicke #MRI ... #Thalamus #NEJM
Disseminated Cysticercosis - Magnetic resonance imaging (MRI) of the head revealed diffuse hyperintense septated cystic lesions
resonance imaging (MRI ... Coronal MRI of the ... Radiology #Pathology #MRI ... Solium #Microscopy #NEJM
Histologic Features and Prevalence of Nonalcoholic Steatohepatitis (NASH). NASH is a potentially progressive type of nonalcoholic
specimens: ballooned hepatocytes ... HCC #Prevalence #NEJM