683 results
Histologic Features and Prevalence of Nonalcoholic Steatohepatitis (NASH). NASH is a potentially progressive type of nonalcoholic
specimens: ballooned hepatocytes ... #Pathology #Epidemiology ... HCC #Prevalence #NEJM
Pathology - Hepatocyte Pigments

Lipofuschin (H&E) 

Alpha-I-antitrypsin globules (PAS-D) 

Mallory's hyaline / Mallory Denk Bodies 

Giant Mitochondria
Pathology - Hepatocyte ... bilirubinostasis (H&E) #Hepatocyte ... #Pigments #Pathology
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
exclusively on hepatocytes ... Within the hepatocyte ... siRNA #Therapy #NEJM
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Synthesis: in hepatocyte ... accumulation in hepatocyte ... from albumin upon hepatocyte ... conjugation in hepatocyte ... reuptake into hepatocyte
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
develop in fatty hepatocytes ... NonAlcoholicFattyLiverDisease #NEJM
Borrelia recurrentis Infection - Spirochetes were visible (arrows), a finding that suggested louseborne relapsing fever #Clinical
fever #Clinical #Pathology ... Smear #Microscopy #NEJM
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Pathologic Red Blood ... Atlas #Microscopy #Pathology ... Robbins & Cotran Pathologic
Excoriated papules with honey-colored crusting were present on the abdomen, back (Panel A), arms, and legs.
Clinical #Derm #Pathology ... Microscopy #Rash #NEJM
African Trypanosomiasis - The examination was notable for the two erythematous lesions, each measuring 3 to
Clinical #Derm #Pathology ... TrypanosomaBrucei #NEJM
Hepatic Portal Venous System Drainage Anatomy
1) Most of the blood from abdominal organs goes into the
is delivered to hepatocytes