2947 results
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
exclusively on hepatocytes ... Within the hepatocyte ... siRNA #Therapy #NEJM
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Synthesis: in hepatocyte ... accumulation in hepatocyte ... from albumin upon hepatocyte ... conjugation in hepatocyte ... reuptake into hepatocyte
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
develop in fatty hepatocytes ... NonAlcoholicFattyLiverDisease #NEJM
Pathology - Hepatocyte Pigments

Lipofuschin (H&E) 

Alpha-I-antitrypsin globules (PAS-D) 

Mallory's hyaline / Mallory Denk Bodies 

Giant Mitochondria
Pathology - Hepatocyte ... bilirubinostasis (H&E) #Hepatocyte
Histologic Features and Prevalence of Nonalcoholic Steatohepatitis (NASH). NASH is a potentially progressive type of nonalcoholic
specimens: ballooned hepatocytes ... HCC #Prevalence #NEJM
Regression of Clubbing after Treatment of Lung Cancer #Clinical #PhysicalExam #Radiology #Clubbing #Regression #LungCancer #CT #NEJM
#PhysicalExam #Radiology ... LungCancer #CT #NEJM
PCI in Acute MI with Cardiogenic Shock. #EBM #Cardiology #CULPRITSHOCK #PCI #VisualAbstract #NEJM
#EBM #Cardiology ... VisualAbstract #NEJM
Hepatic Portal Venous System Drainage Anatomy
1) Most of the blood from abdominal organs goes into the
is delivered to hepatocytes
Goal-Directed Therapy - Evidence Summary of Major Clinical Trials

 - EGDT: NEJM 2001

 - ProCESS: NEJM
Trials - EGDT: NEJM ... - ProCESS: NEJM ... 2014 - ARISE: NEJM ... - ProMlSe: NEJM
Nystagmus from Wernicke’s Encephalopathy - Magnetic resonance imaging of the brain showed T2 hyperintensities involving the
#Clinical #Radiology ... MRI #Thalamus #NEJM