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diagnosis management monoclonal activation alkaline causes classification clinical disorders gammopathy hepatology hodgkins hyophosphatasia leukemia low lymphoma macrophage mas mds mgus
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS) - Differential ... Diagnosis Neurologic-Centered ... Features: POEMS, AL ... #Diagnosis #hematology ... #oncology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
pain • loss of secondary ... • Pernicious anemia ... respiratory failure • Neurologic ... fractures • Dental ... Hyophosphatasia #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... not required in all ... Causes #Workup #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Classified among the secondary ... with leukopenia, anemia ... tests ↑ AST ↑ ALT ... Diagnosis #Management #Hematology ... #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview: ALL ... - infiltrates (anemia ... bone marrow and secondary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... DDX: Rule Out Secondary ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... affects the skin, neurologic ... cognitive impairment, neurologic ... , Elevated AST ALT ... #Diagnosis #Rheumatology
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