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diagnosis hematology coagulation abnormal obstetrics prolonged aflp bleeding bruising dic disease disseminated hellp hemostasis hepatitis hepatology icp intravascular obgyn postpartum
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... PT and the aPTT ... • Reduced liver ... • Massive hemorrhage ... #differential #
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... Early liver disease ... Reduced liver synthesis ... Massive hemorrhage ... #differential #
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... Acral cyanosis • Hemorrhagic ... Fibrinogen: ↓ • PT ... DIC • Severe Liver ... #treatment #management
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
imaging: Hepatic ... extensive necrosis and hemorrhage ... often <5 mg/dL, higher ... obstetrics #hepatitis #comparison ... #differential #
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... Acquired: • Heparin ... liver failure, ... discern these causes ... Bruising #Hemostasis #Differential
Postpartum Hemorrhage - Differential Diagnosis and Management Uterine Atony (80%) - Most PPH Will respond to
Postpartum Hemorrhage ... - Differential ... Diagnosis and Management ... CBC, fibrinogen, PT ... compression (using ultrasound
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