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ANTIBIOTIC SUSCEPTIBILITIES IN INTENSIVE CARE

Antibiotic spectra made simple(r). Version 2, now updated with new bugs &
with new bugs & drugs ... Susceptibilities #ICU ... #CriticalCare ... #Overview #Pharmacology
Delirium in the ICU

Defining delirium
Types of delirium
Consequences of delirium
Reversible causes of delirium
Drug-induced delirium
Non-pharmacologic management of delirium
Pharmacologic
Delirium in the ICU ... causes of delirium Drug-induced ... theABofPharmaC #ICU ... #Delirium #pharmacology ... #management #criticalcare
Checklist for Evaluation of New-Onset Delirium in the ICU

Initial assessment 
 - 
Vital signs, neuro exam
Delirium in the ICU ... - CBC with differential ... - Relevant drug ... Evaluation #Workup #MICU ... #CriticalCare #
Common sodium channel blockers which cause QRS widening.

Anticonvulsants: 
 - Carbamazepine 
Antidysrhythmics:  
 - Group
- Group IA and IC ... Antimalarial drugs ... widening #ECG #EKG #Pharmacology ... Toxicology #Diagnosis #Differential ... #Drugs #Classes
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Addressing the ICU ... A dissociative drug ... No pharmacologic ... (Haldol) - No pharmacologic ... #CriticalCare #
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
common in OR; in MICU ... Inotropes #management #criticalcare ... #summary #comparison ... #table #pharmacology
Shock - Differential Diagnosis Framework
MAP = CO x SVR
Hypovolemic (↓ Intravascular volume):
 • Hemorrhage, dehydration due
Shock - Differential ... adrenal crisis, drugs ... uw_IMresidency #Shock #Differential ... Diagnosis #table #comparison ... #criticalcare
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
of Pregnancy (ICP ... often <5 mg/dL, higher ... obstetrics #hepatitis #comparison ... #differential # ... diagnosis #icp #
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
#diagnosis #differential ... heartfailure #chf #criticalcare ... #icu #clinical ... #pharmacology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
~77-96% - Higher ... BAL GM does not differentiate ... - Frozen ice-pops ... Galactomannan #diagnosis #comparison