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Differential diagnosis of Langerhans cell histiocytosis.
Nodular LCH:
- Sarcoidosis: perilymphatic distribution.
- Metastases: random distribution.
Cystic LCH:
- LAM: round
Differential diagnosis ... Langerhans cell histiocytosis ... : 'signet ring sign ... Diagnosis #Radiology #CTChest ... Comparison #Table #RadiologyAssistant
On the left a chest film of a 19 year old patient with Langerhans cell histiocytosis.
The
Langerhans cell histiocytosis ... most challenging differential ... the central dot sign ... helpfull in the differential ... #Cystic #RadiologyAssistant
On the left three different patients with lung cysts.
From left to right: Lymphangiomyomatosis, LIP and Langerhans
Langerhans cell histiocytosis ... Diagnosis #Radiology #CTChest ... Comparison #LAM #LIP #Histiocytosis ... #RadiologyAssistant
The fourth pattern includes abnormalities that result in decreased lung attenuation or air-filled lesions.
These include:
- Emphysema
-
Langerhans cell histiocytosis ... Radiology #Pulmonary #CTChest ... LowAttenuation #Differential ... Emphysema #SignetRing #RadiologyAssistant
Nodular pattern(2)
1. Sarcoidosis: nodules with perilymphatic distribution, along fissures, adenopathy.
2. TB: Tree-in-bud appearance in a patient
Langerhans cell histiocytosis ... Radiology #HRCT #CTChest ... Comparison #Table #RadiologyAssistant
Upper lung zone preference is seen in:
- Inhaled particles: pneumoconiosis (silica or coal)
- Smoking related diseases
Langerhans cell histiocytosis ... HRCT #ChestCT #Differential ... #Upper #Lower #RadiologyAssistant
Low Attenuation pattern (2) 
1. Centrilobular emphysema: low attenuation areas without walls. Notice the centrilobular artery
Langerhans cell histiocytosis ... Radiology #HRCT #CTChest ... Comparison #Table #RadiologyAssistant
Chest XRay Consolidation Pattern - Differential Algorithm #Diagnosis #Radiology #Pulmonary #CXR #Consolidation #Pattern #Differential #Algorithm #RadiologyAssistant
Chest XRay Consolidation ... Pattern - Differential ... Consolidation #Pattern #Differential ... #Algorithm #RadiologyAssistant
Chest XRay Interstitial Pattern - Differential Algorithm #Diagnosis #Radiology #Pulmonary #CXR #Interstitial #Pattern #Differential #Algorithm #RadiologyAssistant
Chest XRay Interstitial ... Pattern - Differential ... Interstitial #Pattern #Differential ... #Algorithm #RadiologyAssistant
On the left we see a chest film with a typical finger-in-glove shadow.
The HRCT shows focal
left we see a chest ... Radiology #CXR #CTChest ... FingerInGlove #Sign ... #RadiologyAssistant