26 results
Pressors and Inotropes

Norepinephrine
 • alpha1 > beta 1
 • Increase SVR > Inotropy
Vasopressin
 • V1
 •
Pressors and Inotropes ... Increase SVR > Inotropy ... #criticalcare # ... pharmacology #comparison #shock ... #management
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
Vasopressors and Inotropes ... is not desired (e.g ... is not desired (e.g ... #Vasopressors #Inotropes ... #pharmacology #criticalcare
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
Vasopressors and Inotropes ... first agent in shock ... line in septic shock ... #Vasopressors #Inotropes ... Pharmacology #Summary #management
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
Vasopressors and Inotropes ... pressor added in shock ... in refractory shock ... #Vasopressors #Inotropes ... #management #criticalcare
Vasopressors Demystified

Shock comes in many flavors and so do vasopressors. Here’s a OnePager summarizing my approach
Demystified Shock ... Vasopressors #Basics #CriticalCare ... #Management #Pharmacology ... #Comparison #Inotropes
Shock - Diagnosis and Management Summary
 • Hypotension: SBP<90, SBP drop >40, MAP<65 (Normotension, HTN possible
and Management ... telemetry, 12-Lead EKG ... Vasopressors, Inotropes ... #Diagnosis #Management ... #Summary #criticalcare
Severe Heart Failure & Cardiogenic Shock - Management Checklist 
Evaluation 
 - EKG & echocardiography
- Management Checklist ... Rx 4 — Consider inotrope ... considered a weak inotropic ... #HeartFailure #Cardiology ... #Management
DETROIT CARDIOGENIC SHOCK INITIATIVE ALGORITHM

INCLUSION CRITERIA
Acute Myocardial Infarction
 Ischemic Symptoms
 EKG and/or biomarker evidence of AMI
DETROIT CARDIOGENIC SHOCK ... Ischemic Symptoms  EKG ... vasopressors or inotropes ... DCSI #Initiative #Management ... #Cardiology
Clinical Management for Three Common Causes of Shock 
HEMORRHAGIC SHOCK
 • Ensure adequate ventilation and oxygenation.
Clinical Management ... when possible (eg ... vasopressor or inotropic ... #Shock #Management ... #CriticalCare
Myocarditis
Diagnosis 
• Endomyocardial biopsy (gold standard, rarely performed) 
• Clinical presentation 
• Cardiovascular MRI 
Clinical 
•
gallop • Abnormal ECG ... • Cardiogenic shock ... cardiac death Management ... Myocarditis #Diagnosis #Management ... #Cardiology