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oncology rheumatology algorithm allergy chronic disorders gap globulin gpa granulomatosis hemolysis hemolytic immunology intravascular leukemia lupus lymphocytic management mds myelodysplasia
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... thrombocytopenic purpura (TTP ... , lymphoma, idiopathic ... #Causes #differential ... #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of cases) Classification ... Lymphoma Workup ... Immunohistochemical studies (to differentiate ... #lymphoma #diagnosis ... #hematology #oncology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
lymphoma) Neurological ... • Bleomycin Hematologic ... Anemia • Thalessemia ... #dermatology #Differential ... #causes
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
lymphoma SLL ... Diagnosis: • ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... • Goodpasture syndrome ... vasculitis #Dermatologic ... Polyangiitis #GPA #dermatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... changes), high MCV anemia ... or if a primary hematologic ... #Diagnosis #Causes ... #Workup #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... #Diagnosis #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Thrombocytopenia (ITP ... Workup: • Complete ... blood count with differential ... #diagnosis #hematology
Pathergy Summary Overview What is pathergy? Pathergy is an exaggerated skin injury occurring after minor trauma such as
Skin trauma → Erythematous ... • Non-Hodgkin's ... lymphoma What ... #differential # ... allergy #immunology #dermatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... changes (POEMS syndrome ... gastric tumors • Hematology ... anemia • Other ... #diagnosis #hematology
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