Hypercalcemia Differential dermatology skinrash anemia causes classification extravascular workup hodgkins ttp diagnosis syndromes purpura palpable hemolysis

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Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
• Mechanical Trauma (Microangiopathic hemolytic anemia):

Extravascular Causes ... thrombocytopenic purpura ... (TTP), Hemolytic ... #Causes #differential ... #diagnosis #hematology

Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage

Purpura - Differential ... /HUS - Hemolytic ... anemia - Splenomegaly ... CAUSES OF PALPABLE ... Diagnosis #hematology

Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
• Enzyme deficiencies ex. G6PD, pyruvate kinase
• Hemoglobinopathies

Differential Diagnosis ... for Hemolytic Anemia ... : TTP, HUS, DIC, ... #Anemia #Differential ... #Diagnosis #causes

TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A

TTP - Laboratory ... Thrombocytopenic Purpura ... anemia Indirect ... WBC count and differential ... #Workup #Hematology

Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and

GPA causes disease ... reticularis Differential ... • Goodpasture syndrome ... Necrotising vasculitis, extravascular ... #rash #diagnosis

Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It

nodosum • Immune hemolytic ... anemia • Pain ... ) Classification ... Lymphoma Workup ... Immunohistochemical studies (to differentiate

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