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differential rheumatology comparison oncology vasculitis abdominal chronic classification compared disorders erythemas leukemia monoclonal paraproteinemias urticaria vasculitides
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Peripheral blood eosinophilia ... specific symptoms • Eosinophilia ... of eosinophilia ... #hematology #eosinophilia
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
the population Disease ... Autoimmune diseases ... Lymphoproliferative diseases ... Insect stings Disease ... neutrophils and eosinophils
Chronic Abdominal Pain Causes - Differential Diagnosis Framework Many patients with chronic abdominal pain have had prior
Cardiopulmonary disease ... bowel disease ... pseudoobstruction • Eosinophilic ... Adult Still's disease ... Necrotic bowel disease
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Systemic rheumatic diseases ... atherosclerotic disease ... most important diseases ... progressive) EGPA (Eosinophilic ... Polyangiitis): • Eosinophilia
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
• EGPA: - Eosinophilia ... disease, and ocular ... • Kawasaki Disease ... (Granulomatous disease ... atherosclerotic disease
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... anemia due to cold ... Sneddon-Wilkinson disease ... Episodic angioedema+eosinophilia ... Paraproteinemias #Hematology
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
early localized disease ... called "Bazin's disease ... so-called fifth disease ... shows numerous eosinophils ... #dermatology #compared
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... • (Peripheral eosinophilia ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
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