239 results
Cushing Syndrome Testing Algorithm
INDICATIONS FOR TESTING:
 • Suspected Cushing syndrome (central obesity, muscle weakness, refractory hypertension)
Testing:
Cushing Syndrome ... : • Suspected Cushing ... syndrome (central ... Urine Free by LC-MS ... endocrinology #Adrenal #Hyperfunction
Evaluating a Patient with Presumed Cushing Syndrome

#Cushings #Syndrome #Disease #Algorithm #Workup #Dexamethasone #Suppression #Test #diagnosis
with Presumed Cushing ... Syndrome #Cushings ... #Syndrome #Disease
Cushing Syndrome - Hypercortisolism Differential Diagnosis Algorithm

#Cushings #Syndrome #Differential #Diagnosis #Algorithm #disease #endocrinology #Hypercortisolism
Cushing Syndrome ... Diagnosis Algorithm #Cushings ... #Syndrome #Differential
Hypercortisolism (Cushing syndrome) - Simplified Differential Diagnosis Algorithm
Exogenous (ACTH-independent)
Endogenous
 • ACTH-dependent:
    - ACTH-secreting
Hypercortisolism (Cushing ... syndrome) - Simplified ... pituitary adenoma (Cushing ... Hypercortisolism #Cushings ... #syndrome #Differential
Cushing Syndrome - Likelihood Ratios of Physical Exam Findings
Moon facies LR +1.6
Central obesity LR +3.0
Generalized obesity
Cushing Syndrome ... SatyaPatelMD #Cushings ... #Syndrome #Likelihood
Medications associated with neuroleptic malignant syndrome

First-generation and second-generation antipsychotics are dopamine receptor antagonists, which produce a
neuroleptic malignant syndrome ... of dopaminergic hypofunction ... NeurolepticMalignant #Syndrome
Multiple Endocrine Neoplasias (MEN syndromes) 

MEN I
• Hyperparathyroidism 
• Hypercalcemia 
• Possible ZE syndrome 
• Various
Neoplasias (MEN syndromes ... • Possible ZE syndrome ... Acromegaly • Cushing ... syndrome
Cushing Syndrome - Signs and Symptoms
Generalized: Weight gain, Slow healing of cuts, Increased risk of infections,
Cushing Syndrome ... dysfunction (males) #Cushings ... #Syndrome #Signs
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Aldosterone: Liddle's Syndrome ... Carbenoxolone, SAME, Cushing ... Syndrome • HTN ... diuretics, Bartter syndrome ... , Gitelman syndrom
Evaluation of Secondary Hypertension
 • Primary aldosteronism - PRA, PAC
 • Renal artery stenosis - Renal
- TSH, fT4 • Cushing ... syndrome - Late-night ... Mineralocorticoid excess syndromes