25 results
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms
 • Brain: Androgenization effects, Glucocorticoid effects,
Hyperplasia - 21-Hydroxylase ... Reproductive: Gonadal hypofunction ... #Hyperplasia #Hydroxylase
ACTH
LH
Cholesterol
cholesterol desmolase
Pregnenolone
17a-hydroxylase 17 Hydroxyregnenolone
17,20-lyase
3B-hydroxysteroid
dehydrogenase
3B-hydroxysteroid
dehydrogenase
17a-hydroxylase
#Progesterone
17-Hydroxyprogesterone
17,20-lyase
21ß-hydroxylase
21ß-hydroxylase
11-Deoxycorticosterone
11-Deoxycortisol
11ß-hydroxylase
11ß-hydroxylase
#Cortisol
#Dehydroepiandrosterone
#DHEA
3ß-hydroxysteroid
dehydrogenase
个
#Androstenedione
#17B-hydroxysteroid
#dehydrogenase
#Testosterone
#aromatase
#FSH
#Estradiol
#5a reductase
#Corticosterone
aldosterone synthase
#Aldosterone
Angiotensin ||
#Dihydrotestosterone
(DHT)
Pregnenolone 17a-hydroxylase ... 17,20-lyase 21ß-hydroxylase ... 21ß-hydroxylase ... 11ß-hydroxylase ... aromatase #FSH #Estradiol
#LH
#Cholesterol
t
cholesterol desmolase (#thecal cells)
V
3ß-hydroxysteroid
dehydrogenase
Pregnenolone
Progesterone
17a-hydroxylase
17-Hydroxypregnenolone
17,20-lyase
Dehydroepiandrosterone
3ß-hydroxysteroid dehydrogenase
#Androstenedione
17B-hydroxysteroid dehydrogenase
FSH
V
#Testosterone
Đ
#aromatase
(granulosa cells)
V
#Estradiol
Progesterone 17a-hydroxylase ... granulosa cells) V #Estradiol
Secondary causes of Hypertension
 • Medications, Drugs, Chemo: NSAIDS, Steroids, CNI, Alcohol, Cocaine, OCP, Licorice, MAOI,
Syndrome, 11B hydroxylase ... def, 17alpha hydroxylase
This is a quick overview of hormonal acne treatment for the medical student and resident.

Keep in
include: Ethinyl Estradiol ... Norgestimate Ethinyl Estradiol ... Iron) Ethinyl Estradiol ... Drospirenone Ethinyl Estradiol ... acetate/ethinyl estradiol
Cushing Syndrome Testing Algorithm
INDICATIONS FOR TESTING:
 • Suspected Cushing syndrome (central obesity, muscle weakness, refractory hypertension)
Testing:
endocrinology #Adrenal #Hyperfunction
Gynecomastia - Differential Diagnosis a
nd Workup Algorithm
Gynecomastia is common in clinical practice, affecting ~50% of males
Testosterone, HCG, Estradiol
Anastrozole is a Selective non-steroidal aromatase Inhibitor. Used for the treatment of breast cancer in postmenopausal
to estrone and estradiol ... significantly lowers serum estradiol
Medications associated with neuroleptic malignant syndrome

First-generation and second-generation antipsychotics are dopamine receptor antagonists, which produce a
of dopaminergic hypofunction
Feedback Loop: Prolactin (PRL)
 • PRL levels exhibit diurnal, menstrual, and age-related variation
 • TRH has
FSH/LH -> Decr estradiol