7 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
chronic pain • loss ... nephrocalcinosis • CPPD ... collection with EDTA Pathophysiology ... - Premature loss ... Phosphatase: • Other causes
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... bile ducts • Loss ... intralobular bile ducts causes ... PBC Labs: • Alkaline ... diagnosis #workup #hepatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... including liver and hematologic ... ALT, alanine aminotransferase ... hemochromatosis #algorithm ... #diagnosis #management
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
) Pathophysiology ... calcium to form CPP ... swelling, pain, loss ... Deposition #Disease #Rheumatology ... #diagnosis #management
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... • Pathophysiology ... monocyte dysfunction/hypofunction ... injury: Glycocalyx loss ... COMMON CAUSES +
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... trimester pregnancy loss ... • Treatment algorithms ... #diagnosis #management ... #hematology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
hypergammaglobulinemia, and less ... cell lymphoma Pathophysiology ... Thrombocytopenia - Elevated alkaline ... TAFRO #diagnosis #management ... #rheumatology #