292 results
Hyperglycemic Crisis - Algorithm for DKA/HHS

Diagnostic criteria for DKA:
 • pH < 7.3
 • Anion gap
Hyperglycemic Crisis ... #DKA #HHS #Hyperglycemic ... endocrinology #Diabetes #DM2
INSULIN CONVERSION

Total daily dose of insulin (TDD) =
& most type 2 DM ... or at risk for hypoglycemia ... insulin #diabetes #hyperglycemia ... #dm2 #basalinsulin
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
: Weight gain, Hypoglycemia ... Pharmacology #Summary #DM2
Type 2 Diabetes - Screening, Diagnosis and Management Algorithm
Lifestyle  Modifications (Diet and Exercise) -> Start
Recurrent severe hypoglycemia ... relative with DM2 ... associated with DM ... Management #algorithm #DM2
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Does not cause hypoglycemia ... mL/minute/1.73 rm2 ... mL/minute/1.73 m2 ... Pharmacology #Summary #DM2
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
minimal chance of hypoglycemia ... Management #Diabetes #DM2
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
a low risk of hypoglycemia ... Dosing #Diabetes #DM2
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Ketoacidosis (DKA) and Hyperglycemic ... deficit: - Type I DM ... produced - Type II DM ... food binges, etc Hyperglycemia ... #ketoacidosis #hyperglycemic
Comparison of anti-diabetic or anti-hyperglycemic agents

There are numerous anti-hyperglycemic agents available to manage Type 2 diabetes.
anti-diabetic or anti-hyperglycemic ... numerous anti-hyperglycemic ... capability of anti-hyperglycemic ... and compares the hypoglycemia
Diabetes Morning Hyperglycemia - Dawn Phenomenon vs Somogyi Effect 

When patients FBG's are elevated each morning
Diabetes Morning Hyperglycemia ... causes a natural hyperglycemia ... and wake up with hyperglycemia ... response to the hypoglycemia ... prevent the night hypoglycemia