10 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
pain • loss of secondary ... adult population: also ... collection with EDTA Pathophysiology ... mineralization Symptoms ... Hyperlipidemia - Hypercalcemia
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... GrepMed Handbook Clinical ... occurs secondary ... #Endocrinology ... #Treatment #Pathophysiology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Dermatomyositis Clinical ... : • Triad of symptoms ... 5X ULN • AST/ALT ... AST declines > ALT
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... such as internuclear ... progressive decline → Secondary ... • Primary Progressive ... Sclerosis Treatment
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Management Summary Clinical ... bone pain and ↑ ALP ... Hypercalcemia 4 ... . ↑ AST, ALT, and ... /or ALP 5.
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Causes of Secondary ... 109 mm Hg) with clinical ... Vasculitis • Endocrinologic ... Hypothyroidism, Primary ... , Acromegaly, Pheochromocytoma
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
Hyperthyroidism Overview Clinical ... • Insomnia Primary ... thyroiditis Secondary ... Hyperglycemia - ↑ AST/ALT ... #signs #symptoms
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... lateral sclerosis Pathophysiology ... brainstem and multiple ... (3) primary lateral ... column Treatment
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... hyperphosphatemia, hypercalcemia ... renal failure Clinical ... mediators such as ... anterior/posterior MSK
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Cushing's Syndrome ... and Clinical Features ... Cataracts Labs: Hypokalemia ... #signs #symptoms ... #endocrinology