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ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the
Monitor BP, potassium ... , and renal function ... ACEInhibitor #ACEIs #Dosing ... #Conversion #Pharmacology ... #Hypertension #Management
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... and sodium • Dosing ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison
Angiotensin Receptor Blockers 
Recommended Dose Conversions 

Valsartan 
Irbesartan 
Losartan 
Olmesartan 
Telmisartan 
Candesartan 
Azilsartan 
Eprosartan 

A few
, CV benefits, renal ... initiating an ARB ... for increased potassium ... #Conversion #Table ... #Dosing #Pharmacology
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
agents since they are ... not able to effectively ... Note not listed are ... restricted due to hypercalcemia ... #Dosing #Pharmacology
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
aldosterone which does ... sodium, which causes ... Aliskiren, ACEI, ARB ... avoid harmful hyperkalemia ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
ANGIOTENSIN II RECEPTOR ANTAGONIST (ARB) DOSING:
TOOL FOR SWITCHING BETWEEN AGENTS IN CANADA
The information provided is intended
) DOSING: TOOL ... Doses should be ... blood pressure, potassium ... and renal function ... Switching #Equivalent #Table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... Summary Causes ... Monitor potassium ... per day until stable ... #causes #treatment
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... Monitor potassium ... per day until stable ... Dialysis for severe hyperkalemia ... #Summary #causes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Medications: K+, ACEi/ARBs ... only if no clear cause ... Elimination (see Table ... Transient, repeat dose ... #Treatment #potassium
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
DOACs for easier dosing ... dosed BID, and ... patients with good renal ... Anticoagulation #Pharmacology ... #Table