11 results
Hashitoxicosis

‘Leakage’ symptoms of active Hashimoto’s disease

- Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
during the initial hyperthyroid ... thyroiditis that causes ... ‘Leakage’ symptoms ... Hashitoxicosis #Hashimotos #Endocrinology ... #Diagnosis #Pathophysiology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Algorithm ALP ... Intestine - Other causes ... Primary biliary Cholangitis ... #Algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Cirrhosis (PBC) - Summary ... 65 years PBC Pathophysiology ... intralobular bile ducts causes ... PBC Signs and Symptoms ... obstruction • ALP
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
) Differential Diagnosis ... Algorithm DIFFUSE ... contraceptives • Hyperthyroid ... Secondary to Skin Disease ... #Algorithm #causes
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... Summary Epidemiology ... extrapulmonary cases ... decreased reflexes Pathophysiology ... #Management #Summary
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
asymptomatic at diagnosis ... Care focuses on symptom ... management. ... #diagnosis #management ... #summary #Hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... Malnutrition • Wilson's disease ... • hypothyroidism ... mineralization Symptoms ... Phosphatase: • Other causes
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... suspected HH based on symptoms ... of liver disease ... including liver and hematologic ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Griscelli, Purtilo (XLP ... • Autoimmune diseases ... #management #treatment ... #summary #rheumatology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Summary Causes ... Endocrine: Hypo/Hyperthyroidism ... of underlying disease ... #Management #causes