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diagnosis differential glomerulonephritis nephrology rheumatology vasculitis classification membranoproliferative nephrotic progressive proteinuria rapidly renal rpgn syndrome vasculitides
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
dysmorphic RBC, RBC casts ... formation along glomerular ... walls Immune-Complex ... MGPN • Complement ... immune deposits on EM
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... immunofluorescence Immune Complex ... staining): • Low Complement ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... atypical HUS; MPGN ... documented to be a complete ... Nephrocalcinosis causes ... #Algorithm #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tracts Immune Complex ... tract, and often causes ... Vasculitis - Skin, glomeruli ... : - Kidneys: glomerular ... against MPO • Complement
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