7 results
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tracts Immune Complex ... Coronary arteries - Fever ... : • Fevers • ... against MPO • Complement ... #rheumatology #classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Anaphylaxis, Hay fever ... Antigen-antibody complex ... Antigen-antibody complexes ... they activate complement ... allergy #table #classification
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
, seasonal hay fever ... antigen, leading to complement ... Antigen-antibody complexes ... Complement activation ... #Classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
deposit of immune complexes ... Types: • Type ... • Low serum C4 complement ... • Vasculitis ... #classification
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Infection - Vasculitis ... Red Flags: • Fever ... deficiency Work ... Up: • Complete
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... anti-Smith Ab, low complements ... Skin Disease Classification ... Kikuchi disease • Type-I ... to: Arthritis, Fever
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
Diagnostic Workup ... guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis ... Types of MGRS-Associated