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diagnosis classification differential rheumatology vasculitis allergy bands basophils comparison cryoglobulinemia cryoglobulins dermatology gammopathy hematology hypersensitivity leucocytosis leukemoidreaction mds mgrs monoclonal
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Allergen-specific lgE causes ... Anaphylaxis, Hay fever ... Antigen-antibody complex ... Antigen-antibody complexes ... they activate complement
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
deposit of immune complexes ... injury and end-organ ... • They can cause ... Cryoglobulins Cause ... • Low serum C4 complement
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tracts Immune Complex ... tract, and often causes ... Coronary arteries - Fever ... Vasculitis: • Fevers ... against MPO • Complement
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... Red Flags: • Fever ... deficiency Work ... Up: • Complete
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... formed or don’t work ... skin that are caused ... agents given to organ ... Workup: • Complete
Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
depending on cell type ... infection, sepsis, organ ... neutropenia: typhoid fever ... Morphologically: absence of complete ... the underlying cause
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
kidney disease caused ... • Leads to organ ... Diagnostic Workup ... tubulopathy) - Complement ... vasculitis Types
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