6 results
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... of Hypocomplementemic ... antibiody -> Immune Complex ... Formation - Complement ... > Incr Immune Complex
Algorithm for the differentiation between simple and complex febrile seizures. Guidelines for evaluation of each. #Diagnosis
Algorithm for the ... between simple and complex ... FebrileSeizure #Fever ... #Workup #Simple ... #Complex
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... immunofluorescence Immune Complex ... staining): • Low Complement ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
, seasonal hay fever ... antigen, leading to complement ... Antigen-antibody complexes ... Complement activation ... Classification #Pathophysiology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tracts Immune Complex ... Urticaria and hypocomplementemia ... Coronary arteries - Fever ... Vasculitis: • Fevers ... against MPO • Complement
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Red Flags: • Fever ... deficiency Work ... Up: • Complete ... Differential #Diagnosis #Algorithm