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diagnosis differential rheumatology types allergy comparison cryoglobulinemia cryoglobulins dermatology gammopathy glomerulonephritis hypersensitivity mgrs monoclonal petechiae petechial physicalexam progressive rapidly rash
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tracts Immune Complex ... tract, and often causes ... : • Fevers • ... against MPO • Complement ... #rheumatology #classification
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... immunofluorescence Immune Complex ... staining): • Low Complement ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
: • Fevers • Fatigue ... pauci-immune GN Immune Complex ... tract, and often causes ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Allergen-specific lgE causes ... Anaphylaxis, Hay fever ... Antigen-antibody complex ... they activate complement ... allergy #table #classification
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... Red Flags: • Fever ... deficiency Work ... Up: • Complete
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
deposit of immune complexes ... • They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... diagnosis #types #classification
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
kidney disease caused ... Diagnostic Workup ... guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis
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