13 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis, type ... 1 (50%-80%), type ... #Low #Complement ... #differential #hematology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
lgE causes mast-cell ... antigens, leading to complement ... they activate complement ... #allergy #table ... #classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... #classification ... #rheumatology #
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... for secondary causes ... are asthma, allergy ... #diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... • RBC Membrane Disorder ... RBC Metabolism Disorder ... Non-lmmune #Anemia #Classification ... #Causes #Hematology
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... protein receptor type ... activin A receptor type ... multifactorial mechanisms Hematologic ... #Differential #Causes
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Lymphoproliferative Disorders ... symptoms, unexplained hematologic ... Diagnosis and classification ... to 50% of PTLD cases ... Lymphoproliferative #Disorders
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... #classification
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Pancytopenia is a hematologic ... or a peripheral type ... that involves disorders ... These causes could
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
eosinophilia Secondary Causes ... : - Allergic disorders ... - Immunologic disorders ... HES Types: - Myeloproliferative ... eosinophilia #diagnosis #hematology