12 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... cellular antigen, leading ... to complement activation ... Complement activation ... Hypersensitivity #Types #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
lgE causes mast-cell ... cell antigens, leading ... to complement activation ... they activate complement ... #table #classification
Tinnitus - Subjective (heard only by patient) - 90% - Differential Diagnosis Algorithm
Unilateral On Audiogram -
Differential Diagnosis Algorithm ... • Metabolic Causes ... : Thyroid Dysfunction ... Differential #Diagnosis #Algorithm ... #Causes
Conductive Hearing Loss - Differential Diagnosis Algorithm

Normal Otoscopy - Middle Ear:
 • Otosclerosis
 • Congenital (Ossicular
Conductive Hearing ... Differential Diagnosis Algorithm ... Eustachian Tube Dysfunction ... Eustachian Tube Dysfunction ... #Causes
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... Differential Diagnosis Algorithm ... perfringens - Complement-Mediated ... - Mechanical Shearing ... #Causes #Hematology
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
degranulation, leading ... cell surfaces causes ... immune reaction, leading ... causes development ... #Types #Classification
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
permanent organ dysfunction ... • Excessive heating ... maintained fever CAUSES ... transfusion • Allergic ... #Differential #Causes
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... diagnosis #types #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology #classification
Tinnitus - Objective (can be heard/auscultated) - 10% - Differential Diagnosis Algorithm
Vascular - Arterial:
 • Atherosclerosis
Differential Diagnosis Algorithm ... Eustachian Tube Dysfunction ... Tinnitus #Ringing #hearing ... Differential #Diagnosis #Algorithm ... #Causes