7 results
Allergic Contact Dermatitis 
- Erythematous, indurated, scaly plaques 
- T-cell mediated, delayed-type hypersensitivity response to exogenous
Allergic Contact ... mediated, delayed-type ... hypersensitivity ... Contact #Dermatitis #Allergic ... #Allergy #Dermatology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... When the specific allergen ... antigen, leading to complement ... Complement activation ... sclerosis #Hypersensitivity
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis, type ... 1 (50%-80%), type ... #Low #Complement ... #differential #hematology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
of hypersensitivity ... Mechanism of Action: Allergen-specific ... antigens, leading to complement ... they activate complement ... #allergy #table
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
Type II Hypersensitivity ... activates the complement ... cell surfaces #Type2 ... #Type2 #HypersensitivityReaction ... #Allergy #Immunology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Types: • Type ... • Type III Often ... • Low serum C4 complement ... vasculitis • Hypersensitivity ... classification #rheumatology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Secondary Causes: - Allergic ... disorders - Drug hypersensitivity ... disorders HES Types ... eosinophilia #diagnosis #hematology