6 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... - CHAMPS Mnemonic ... 1 (50%-80%), type ... #Low #Complement ... #CHAMPS #Mnemonic
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Types: • Type ... • Low serum C4 complement ... #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology #classification
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
SPEP+free light chains ... or alternative complement ... infections are common causes ... for ANCA-related vasculitis ... cryoglobulinemias (types
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
or alternative complement ... SPEP+free light chains ... infections are common causes ... for ANCA-related vasculitis ... cryoglobulinemias (types
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
kidney disease caused ... guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis ... Types of MGRS-Associated