10 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... S - Systemic Lupus ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic Lupus ... Acute cutaneous lupus ... anticoagulant • Complement ... #EULARACR #Classification
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
thiazidic, PPI, ACE ... 90% - Low complement ... Discontinuation of causal ... 80% - Low complement ... #sle #comparison
Chest Pain / ACS Evaluation Algorithm
Algorithm that attempts to the use history taking (guided by LRs),
Chest Pain / ACS ... Evaluation Algorithm ... Algorithm that ... Diamond-Forrester classification ... physical activity - Nausea
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Post-strep GN, Lupus ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Allergen-specific lgE causes ... they activate complement ... glomerulonephritis, Systemic lupus ... allergy #table #classification ... #comparison
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... inflammation Others: • Lupus ... systemic lupus ... against MPO • Complement ... #rheumatology #classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... (e.g. systemic lupus ... diagnosis #types #classification
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... Epidemiology: -10% of all lupus ... thiazidic, PPI, ACE ... 90% - Low complement ... Discontinuation of causal
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Causes of Hyperkalemia ... combination with ACE ... diseases: syßtemic lupus ... High #Potassium #Classification ... #Causes