6 results
diagnosis rheumatology management druginduced lupus comparison differential dil disease gammopathy mgrs monoclonal phenotypes related renal significance sle table vasculitides workup
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
with response to treatment ... rheumatoid factor), ± hypocomplementemia ... No necrosis, No vasculitis ... + cells" Treatment ... maintenance with GCs
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology #classification
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
IGG-4 RELATED DISEASE ... aortitis, mimics vasculitis ... - ↑ IgE, ↓ complement ... • Classification ... : 2019 ACR/EULAR
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
thiazidic, PPI, ACE ... - ANA > 95% (IgG ... 90% - Low complement ... 80% - Low complement ... life-threatening • Treatment
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
thiazidic, PPI, ACE ... - ANA > 95% (IgG ... 90% - Low complement ... Discontinuation of causal ... rheumatology #diagnosis #treatment
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
kidney disease caused ... guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis ... microangiopathy Treatment
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